First participants dosed in Dicot's phase 1 trial

Dicot has recently started the first clinical trial with its potency drug candidate LIB-01. The primary objective of the study is to evaluate the safety of LIB-01 and consists of two parts: single dosing and repeated dosing. The recruitment of healthy participants for the first part of the study, the single dosing, started immediately after approval from the authorities and today the first participants have been dosed. The trial is performed at the University Hospital in Uppsala, where the company's partner CTC has its clinic.

The single-dose part of the study involves around 50 participants, divided into different dose groups and where the doses are gradually increased in subsequent groups. After dosing, participants are admitted for a period of three days during which frequent safety assessments are conducted, including blood sample collection, blood pressure monitoring, and ECG, all of which are standard procedures in this type of first-in-human study.

The single dosing will be followed by the second part of the study where repeated doses are given to each of the participants. The entire phase 1 trial is double blinded and placebo-controlled, which means that some participants receive LIB-01 and some receive placebo and that neither the participant nor the investigator know who receives LIB-01 and who receives placebo.

"The start of the study has gone completely according to plan and it feels fantastic that the first dose of LIB-01 has now been administrated. We are so grateful to all study participants who contribute to significant research through this. It brings us closer to a new improved treatment for all men and couples who suffer from erectile problems", states Dicot´s CEO, Elin Trampe.